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in-body medical device 2

ingestible medical device 2

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miniature actuator 2

wireless capsule endoscopy 2

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Key words: Binocular endoscope 1

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advance bioprocess development and biomanufacturing 1

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Analysis of actuating mechanics characteristics for a flexible miniature robot system

YU Lianzhi, YAN Guozheng, MA Guanying, ZAN Peng

Frontiers of Mechanical Engineering 2008, Volume 3, Issue 1,   Pages 66-70 doi: 10.1007/s11465-008-0006-5

Abstract: Based on the inchworm movement, a miniature endoscope inspection robot system with a flexible structure

Keywords： calculation     consistent     endoscope inspection     electro-pneumatic     miniature endoscope    

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An autonomous miniature wheeled robot based on visual feedback control

CHEN Haichu

Frontiers of Mechanical Engineering 2007, Volume 2, Issue 2,   Pages 197-200 doi: 10.1007/s11465-007-0033-7

Abstract: Using two micro-motors, a novel omni-direction miniature wheeled robot is designed on the basis of the

Keywords： measuring     distance     autonomous locomotion     advantage     navigation    

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Development of mobile miniature natural gas liquefiers

Yanxing ZHAO, Maoqiong GONG, Haocheng WANG, Hao GUO, Xueqiang DONG

Frontiers in Energy 2020, Volume 14, Issue 4,   Pages 667-682 doi: 10.1007/s11708-020-0695-y

Abstract: In consideration of the above, this paper reviews the development of mobile miniature NG liquefiers in

Keywords： natural gas     mobile miniature liquefiers     mixed refrigerant cycle     vapor liquid equilibrium     heat transfer    

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A miniature triaxial apparatus for investigating the micromechanics of granular soils with

Zhuang CHENG, Jianfeng WANG, Matthew Richard COOP, Guanlin YE

Frontiers of Structural and Civil Engineering 2020, Volume 14, Issue 2,   Pages 357-373 doi: 10.1007/s11709-019-0599-2

Abstract: The development of a miniature triaxial apparatus is presented.The apparatus allows for triaxial testing of a miniature dry sample with a size of (diameter height

Keywords： triaxial apparatus     X-ray μCT     in situ test     micro-scale mechanical behavior     granular soils    

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Cavitation in semi-open centrifugal impellers for a miniature pump

LUO Xianwu, LIU Shuhong, ZHANG Yao, XU Hongyuan

Frontiers in Energy 2008, Volume 2, Issue 1,   Pages 31-35 doi: 10.1007/s11708-008-0011-8

Abstract: Cavitation in miniature pumps was investigated experimentally for two semi-open centrifugal impellersThe results show that the miniature pumps have similar cavitation performances as an ordinary-size pumpshow that uniform flow upstream of the impeller inlet will improve the cavitation performance of a miniature

Keywords： cavitation performance     semi-open impeller     increased     two-dimensional     efficiency    

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Application of endoscopic techniques in orbital blowout fractures

Shu Zhang, Yinwei Li, Xianqun Fan

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 328-332 doi: 10.1007/s11684-013-0271-5

Abstract:

Minimally invasive surgical techniques, particularly endoscopic techniques, have revolutionized otolaryngeal surgery. Endoscopic techniques have been gradually applied in orbital surgery through the sinus inferomedial to the orbit and the orbital subperiosteal space. Endoscopic techniques help surgeons observe fractures and soft tissue of the posterior orbit to precisely place implants and protect vital structures through accurate, safe, and minimally invasive approaches. We reviewed the development of endoscopic techniques, the composition of endoscopic systems for orbital surgery, and the problems and developmental prospects of endoscopic techniques for simple orbital wall fracture repair.

Keywords： orbital fractures     endoscope     restoration     surgery    

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A Miniature Meta-Optical System for Reconfigurable Wide-Angle Imaging and Polarization-Spectral Detection

Fei Zhang,Minghao Liao,Mingbo Pu,Yinghui Guo,Lianwei Chen,Xiong Li,Qiong He,Tongtong Kang,Xiaoliang Ma,Yuan Ke,Xiangang Luo,

Engineering doi: 10.1016/j.eng.2023.07.008

Abstract: demonstration, the simultaneous implementation of wide-angle imaging and polarization-spectral detection in a miniature

Keywords： Metasurfaces     Reconfigurable     Imaging     Spectral    

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Advanced Bioprocess Development and Manufacturing Technologies in High-Throughput Miniature Bioreactors

Jiao Peng, Chen Biqiang

Strategic Study of CAE 2016, Volume 18, Issue 4,   Pages 44-50 doi: 10.15302/J-SSCAE-2016.04.007

Abstract:

In recent years, the importance of rapid response time to virulent infectious disease is widely recognized. However, the traditional technologies for bioprocess development and manufacturing will not succeed in winning this war. US healthcare companies and related organizations including US Department of Human Health and Service, proposed and started working on the next generation of technology platforms for advanced bioprocess development and manufacturing (ABDM).The development of ABDM is to significantly reduce the timeframe for bioprocess development and manufacturing, making it possible to promptly respond to outburst of pandemic influenza and prevent it from outspreading. Meanwhile, the development of precision medicine also presents new demands to the biopharmaceutical industry. With the demand of small-scale production and fast turn-around time of precision medicine, the duration of development and manufacturing needs to be accelerated significantly. At the same time, the number of sub-groups of the product would increase, and the batch sizes and amount of final product would decrease, as well. To satisfy the demands of small-scale production and fast turnaround time of ABDM, micro- and mini-bioreactor is the key equipment. The major technologies of ABDM include high throughput screening and process development based on micro- and mini-bioreactors, disposable technology, modular unit operations and flexible manufacturing. The development of ABDM will directly strengthen the National Security, improve the welfare of the people, and it also provides great social and economic values. The impact of this platform will radiate to the entire biomanufacture industry, and open a whole new era for the bioprocess development and bio-manufacturing.

Keywords： advance bioprocess development and biomanufacturing     virulent infectious disease     precision medicine     miniature    

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Capsule endoscopy—A mechatronics perspective

Lin LIN, Mahdi RASOULI, Andy Prima KENCANA, Su Lim TAN, Kai Juan WONG, Khek Yu HO, Soo Jay PHEE

Frontiers of Mechanical Engineering 2011, Volume 6, Issue 1,   Pages 33-39 doi: 10.1007/s11465-011-0203-5

Abstract: circuit technology, wireless communication, and sensor technology have opened the door for development of miniature

Keywords： wireless capsule endoscopy     ingestible medical device     in-body medical device     medical robot     miniature actuator    

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A Confocal Endoscope for Cellular Imaging Article

Jiafu Wang,Min Yang,Li Yang,Yun Zhang,Jing Yuan,Qian Liu,Xiaohua Hou,Ling Fu

Engineering 2015, Volume 1, Issue 3,   Pages 351-360 doi: 10.15302/J-ENG-2015081

Abstract: Here, we present the design and construction of a confocal endoscope based on a fiber bundle with 1.4fiber-optic probe has a diameter of 2.6 mm that is compatible with the biopsy channel of a conventional endoscopeThe prototype of a confocal endoscope has been used to observe epithelial cells of the gastrointestinalIn addition, the confocal endoscope can be used for translational studies of epithelial function in order

Keywords： cellular resolution     confocal endoscopy     optical biopsy    

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A three-dimensional measurement method for binocular endoscopes based on deep learning Research Article

Hao YU, Changjiang ZHOU, Wei ZHANG, Liqiang WANG, Qing YANG, Bo YUAN,yuanbo@zju.edu.cn

Frontiers of Information Technology & Electronic Engineering 2022, Volume 23, Issue 4,   Pages 653-660 doi: 10.1631/FITEE.2000679

Abstract: In the practice of clinical endoscopy, the precise estimation of the lesion size is quite significant for diagnosis. In this paper, we propose a three-dimensional (3D) measurement method for binocular endoscopes based on , which can overcome the poor robustness of the traditional binocular matching algorithm in texture-less areas. A simulated binocular image dataset is created from the target 3D data obtained by a 3D scanner and the binocular camera is simulated by 3D rendering software to train a model for 3D measurement. The experimental results demonstrate that, compared with the traditional binocular matching algorithm, the proposed method improves the accuracy and disparity map generation speed by 48.9% and 90.5%, respectively. This can provide more accurate and reliable lesion size and improve the efficiency of endoscopic diagnosis.

Keywords： Key words: Binocular endoscope     Three-dimensional measurement     Deep learning     Disparity estimation    

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The New Development of Heavy Force Measurement Technique —Adhesion and Super-miniature Type of Heavy

Shen Jiuheng

Strategic Study of CAE 2001, Volume 3, Issue 10,   Pages 22-27

Abstract: The super-miniature adhesion type of heavy force sensor invented by the auther and its engineering application

Keywords： heavy equipment     heavy force sensor     supporting type     adhesion type     resistance strain gauge     division measurement    

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Ingestible wireless capsules for enhanced diagnostic inspection of gastrointestinal tract

Mahdi RASOULI, Andy Prima KENCANA, Van An HUYNH, Eng Kiat TING, Joshua Chong Yue LAI, Kai Juan WONG, Su Lim TAN, Soo Jay PHEE

Frontiers of Mechanical Engineering 2011, Volume 6, Issue 1,   Pages 40-44 doi: 10.1007/s11465-011-0204-4

Abstract:

Wireless capsule endoscopy has become a common procedure for diagnostic inspection of gastrointestinal tract. This method offers a less-invasive alternative to traditional endoscopy by eliminating uncomfortable procedures of the traditional endoscopy. Moreover, it provides the opportunity for exploring inaccessible areas of the small intestine. Current capsule endoscopes, however, move by peristalsis and are not capable of detailed and on-demand inspection of desired locations. Here, we propose and develop two wireless endoscopes with maneuverable vision systems to enhance diagnosis of gastrointestinal disorders. The vision systems in these capsules are equipped with mechanical actuators to adjust the position of the camera. This may help to cover larger areas of the digestive tract and investigate desired locations. The preliminary experimental results showed that the developed platform could successfully communicate with the external control unit via human body and adjust the position of camera to limited degrees.

Keywords： wireless capsule endoscopy     ingestible medical device     in-body medical device     miniature actuator     medical    

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Title Author Date Type Operation

Analysis of actuating mechanics characteristics for a flexible miniature robot system

YU Lianzhi, YAN Guozheng, MA Guanying, ZAN Peng

Journal Article

An autonomous miniature wheeled robot based on visual feedback control

CHEN Haichu

Journal Article

Development of mobile miniature natural gas liquefiers

Yanxing ZHAO, Maoqiong GONG, Haocheng WANG, Hao GUO, Xueqiang DONG

Journal Article

A miniature triaxial apparatus for investigating the micromechanics of granular soils with

Zhuang CHENG, Jianfeng WANG, Matthew Richard COOP, Guanlin YE

Journal Article

Cavitation in semi-open centrifugal impellers for a miniature pump

LUO Xianwu, LIU Shuhong, ZHANG Yao, XU Hongyuan

Journal Article

Application of endoscopic techniques in orbital blowout fractures

Shu Zhang, Yinwei Li, Xianqun Fan

Journal Article

A Miniature Meta-Optical System for Reconfigurable Wide-Angle Imaging and Polarization-Spectral Detection

Fei Zhang,Minghao Liao,Mingbo Pu,Yinghui Guo,Lianwei Chen,Xiong Li,Qiong He,Tongtong Kang,Xiaoliang Ma,Yuan Ke,Xiangang Luo,

Journal Article

Advanced Bioprocess Development and Manufacturing Technologies in High-Throughput Miniature Bioreactors

Jiao Peng, Chen Biqiang

Journal Article

Capsule endoscopy—A mechatronics perspective

Lin LIN, Mahdi RASOULI, Andy Prima KENCANA, Su Lim TAN, Kai Juan WONG, Khek Yu HO, Soo Jay PHEE

Journal Article

A Confocal Endoscope for Cellular Imaging

Jiafu Wang,Min Yang,Li Yang,Yun Zhang,Jing Yuan,Qian Liu,Xiaohua Hou,Ling Fu

Journal Article

A three-dimensional measurement method for binocular endoscopes based on deep learning

Hao YU, Changjiang ZHOU, Wei ZHANG, Liqiang WANG, Qing YANG, Bo YUAN,yuanbo@zju.edu.cn

Journal Article

The New Development of Heavy Force Measurement Technique —Adhesion and Super-miniature Type of Heavy

Shen Jiuheng

Journal Article

Ingestible wireless capsules for enhanced diagnostic inspection of gastrointestinal tract

Mahdi RASOULI, Andy Prima KENCANA, Van An HUYNH, Eng Kiat TING, Joshua Chong Yue LAI, Kai Juan WONG, Su Lim TAN, Soo Jay PHEE

Journal Article